Beilstein J. Nanotechnol.2019,10, 2152–2162, doi:10.3762/bjnano.10.208
, which are also exhibited by the SmartLipids, are reviewed. These include the restauration of the protective lipid skin barrier (anti-pollution effect), penetrationenhancement by occlusion (invisible patch effect) and the option to control the release of active agents for optimized biological effect and
inclusion; nanostructured lipid carriers (NLCs); penetrationenhancement; skin occlusion; SmartLipids; solid lipid nanoparticles (SLNs); Introduction
To meet the increasing expectations and demands of consumers in personal care and cosmetics, as well of patients in medical care, dermal delivery systems are
agents, e.g., retinol as a classical example;
restoration of the natural skin barrier (recently in focus in the framework of “anti-pollution” strategies);
penetrationenhancement and increased bioavailability allowing for a reduced application frequency, enabling the use of active agents that could not
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Figure 1:
Simple representation of the structure of SmartLipids. The mixture of structurally very different s...